We specialized in: Radiopharmaceuticals

Computational infrastructure for high-stakes pharma

AI for pharmaceutical discovery, development, and de-risking.

Our AI platform

How can Epitorix help you?

One AI stack. Three ways to work with us.

One intelligence layer. Multiple ways to engage with Epitorix. Build therapies. Back innovation. De-risk development.

Who we are

Who we are

Epitorix is an intelligence platform and product company for pharma. We build AI models, applications, and internal drug programs that help teams discover therapies, evaluate risk, and make better decisions.

Driven by biology. Powered by AI.

ModelsDataWorkflowsApplicationsInternal programs

Ligand ranking

Any ligand in.
One ranked list out.

Epitorix developed a deep-learning model that ranks any ligand input. Give it 100 generated ligands — from any generative model, or from your own library — and in internal benchmarks it recovers more than 80% of your true top ligands.

Measured in internal benchmarks. A preprint describing the evaluation is forthcoming.

Every class

It works across small molecules, peptides, non-canonical peptides, macrocycles, antibodies, nanobodies, mini-proteins and DNA/RNA ligands.

Not just ranking

Epitorix can generate and rank. You are equally free to bring your own ligands and have them ranked.

Kd evaluation at scale

Epitorix predicts Kd at scale: Pearson R = 0.70 for small molecules and 0.84 for peptides, screening thousands in minutes. High speed ranking at ~1,000 molecules/s.

Science behind the scene

Problem Solved Faster, cheaper, and more precise

Traditional development can take years and millions of dollars before major safety risks become visible. Epitorix predicts biodistribution, organ risk, and cell-type risk earlier, enabling faster and lower-cost candidate optimization before clinical trials.

Traditional Approach

3-5 Years

to reach preclinical

$5-$10M

  • 1Preclinical development
  • 2Clinical trials begin
  • 3Toxicity discovered late

Up to 100x

lower cost

Up to 65x

faster

Epitorix

4-6 Weeks

to reach preclinical

Up to $100K

  • Predict PK, PD & biodistribution
  • Identify organ & cell-type risk
  • Optimize candidate before clinic
  • Enter clinic with greater confidence

Generation

Targeted candidate generation

Traditional mRNA/phage display creates noisy, non-site-specific libraries and can take months. Epitorix generates ~10,000 high-quality site- and target-specific candidates with far less biological noise.

Traditional

mRNA/Phage Display

AI Structure-Guided

Generation

~6 Months
Saved to Generate High Quality Candidate
~60%
Success Rate Increase

Higher accuracy and target specificity

Off-target

Proteome-wide off-target prediction

Traditional microarrays are limited by protein coverage, biological noise, cost, and long timelines. Epitorix predicts protein off-targets for targets, small molecules, and peptides in about 1 hour with >90% accuracy.

NCAM1SSTR1CXCR4ATRNL1PRKG1BCL2FXYD2PLPP1NCAM1SSTR1CXCR4ATRNL1PRKG1BCL2FXYD2PLPP1

Highly Accurate Off-Target Prediction

In retrospective analyses, our model achieved over 90% accuracy in detecting known off-target interactions.

0%

F1 · Binder

0%

R · Peptide

0%

R · Small-Molecule

~1 hour
Epitorix: proteome-scale
>90%
accuracy in detecting known off-target interactions

Traditional methods: expensive and limited number of panels

Ranking

Kd evaluation at scale

SPR and BLI require synthesis and wet-lab testing and can take months. Molecular dynamic and FEP+ need multiple hours per prediction. Epitorix predicts Kd at scale: Pearson R = 0.70 for small molecules and 0.84 for peptides, screening thousands in minutes.

Peptides

R = 0.84

Small molecules

R = 0.70

~1,000
molecules/s — high speed ranking

Comparable accuracy to costly computational methods.

Biodistribution and organ/cell at risk

Predict side-effects before trials

Traditional programs often discover toxicity only after clinical testing begins. Epitorix predicts PK, PD, biodistribution, cell-type risk, and organ risk to optimize radiotherapeutics before side effects emerge.

  • KidneyHighKidney proximal tubular cells
  • LiverModerateLiver sinusoidal cells
  • MarrowModerateHematopoietic stem & progenitor cells
  • SalivaryLowSalivary acinar cells
Earlier
safety insight
Optimize
before the clinic

More about EPiQ™

  • No-code
  • Fast and reliable
  • High-end technology
  • Transparent process

PharmPhax™

A Reliable System to De-Risk Radiopharmaceutical Industrial Investment

We put certainty and intelligence at your fingertips

0%

Accuracy

Pipeline & Show cases

Accelerating Toward the Clinic

We are generating the next pharmaceutical using our pipeline

  1. Design the Lead

    Completed · Q1 2026

  2. Optimize the Lead

    Completed · Q1 2026

  3. In Vitro Binding Assay

    Completed · Q1 2026

  4. In Vivo Validation

    In Progress · Q2 2026

  5. Translational & Regulatory Step

    Upcoming · Q3 2026

  6. Clinical Trial

    Upcoming · Q4 2026

Target

In Vivo Validation

HER2

Experimental Kd

2.1 nM

In Progress · Q2 2026

Target

In Vivo Validation

TROP2

Experimental Kd

8.5 nM

In Progress · Q2 2026

Target

In Vivo Validation

CD38

Experimental Kd

19.5 nM

In Progress · Q2 2026

Target

In Vivo Validation

PD-L1

Experimental Kd

45 nM

In Progress · Q2 2026

/FAQ

Clear Answers to Your Common Questions

  • Radiopharmaceutical development is slow, expensive, and fragmented. Critical questions about target suitability, binding affinity, off-target interactions, biodistribution, organ exposure, and cell-specific toxicity are often evaluated through separate experimental workflows. Epitorix integrates these decisions into an AI-driven discovery and de-risking ecosystem designed to identify stronger candidates and potential development risks earlier.

Contact

Bring us a target.

Move from disease biology to a collaborative end-to-end program—from target discovery through lead generation—combining Epitorix intelligence with the scientists guiding the development path.

Target discoveryEnd-to-end

/Contact

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